Eosinopenia of Acute Infection

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Eosinopenia of acute infection: Production of eosinopenia by chemotactic factors of acute inflammation.

One distinctive aspect of the response to acute inflammation involves a rapid and persistent decrease in the numbers of circulating eosinophils, yet the mechanisms of this eosinopenia are undefined. One possibility is that the abrupt eosinopenia may be the result of release of small amounts of the chemotactic factors of acute inflammation into the circulation. These studies were designed to exa...

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The spleen and blood eosinopenia.

Within a few hours of injury or burning the number of eosinophils in the blood falls progressively to reach low or zero values and this eosinopenia (Fig. 1) lasts up to a few days (Laragh and Almy, 1948; Roche, Thorn, and Hills, 1950; Hardy, 1950; Sevitt, 1951, 1954; Evans and Butterfield, 195 1). The endocrine control of eosinopenia is known to be due to release of adrenocortical hormones thro...

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Eosinopenia as a marker of infection in patients with sickle cell anaemia: A preliminary report

Neutrophilia is a useful marker of infection in many clinical settings but it is of limited value in SCA patients in whom neutrophilia with left shift is common even in steady state in the absence of infection. We hypothesize that eosinopenia may be a more reliable marker of infection in SCA patients. Retrospective analysis of the neutrophil and eosinophil counts of SCA patients in steady state...

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Is eosinopenia a reliable marker of sepsis?

To test this hypothesis, we reviewed 191 patients (age >18 years, with a minimum ICU stay of 24 hours) admitted to the medical ICU of our hospital. We exuded HIV-infected patients and those with hematological malignancies. Total leukocyte and eosinophil count (EC) were measured at ICU admission. The results are shown in Table 1. Although the EC was lower and the proportion of patients with eosi...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1980

ISSN: 0021-9738

DOI: 10.1172/jci109789